Coupled mutation finder: A new entropy-based method quantifying phylogenetic noise for the detection of compensatory mutations

BACKGROUND: The detection of significant compensatory mutation signals in multiple sequence alignments (MSAs) is often complicated by noise. A challenging problem in bioinformatics is remains the separation of significant signals between two or more non-conserved residue sites from the phylogenetic...

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Detalles Bibliográficos
Autores principales: Gültas, Mehmet, Haubrock, Martin, Tüysüz, Nesrin, Waack, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577461/
https://www.ncbi.nlm.nih.gov/pubmed/22963049
http://dx.doi.org/10.1186/1471-2105-13-225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577461/
https://www.ncbi.nlm.nih.gov/pubmed/22963049
http://dx.doi.org/10.1186/1471-2105-13-225

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