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Coupled mutation finder: A new entropy-based method quantifying phylogenetic noise for the detection of compensatory mutations
BACKGROUND: The detection of significant compensatory mutation signals in multiple sequence alignments (MSAs) is often complicated by noise. A challenging problem in bioinformatics is remains the separation of significant signals between two or more non-conserved residue sites from the phylogenetic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577461/ https://www.ncbi.nlm.nih.gov/pubmed/22963049 http://dx.doi.org/10.1186/1471-2105-13-225 |