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Detection of rtN236T mutation associated with adefovir dipivoxil resistance in Hepatitis B infected patients with YMDD mutations in Tehran

BACKGROUND OBJECTIVES: The risk of adefovir dipivoxil resistance emergence has increased in lamivudine-resistant hepatitis B infected patients. The mutations known as causing adefovir resistance, rtN236T and rtA181V/T, are detected within the D and B functional domain of the HBV polymerase, respecti...

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Detalles Bibliográficos
Autores principales: Monavari, Seyed Hamidreza, Keyvani, Hossein, Mollaie, Hamidreza, Roudsari, Rouhollah Vahabpour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577563/
https://www.ncbi.nlm.nih.gov/pubmed/23467016