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Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for persona...

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Detalles Bibliográficos
Autores principales: Gonzalez de Castro, D, Clarke, P A, Al-Lazikani, B, Workman, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577635/
https://www.ncbi.nlm.nih.gov/pubmed/23361103
http://dx.doi.org/10.1038/clpt.2012.237