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Personalized Cancer Medicine: Molecular Diagnostics, Predictive biomarkers, and Drug Resistance
The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers for persona...
Autores principales: | Gonzalez de Castro, D, Clarke, P A, Al-Lazikani, B, Workman, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577635/ https://www.ncbi.nlm.nih.gov/pubmed/23361103 http://dx.doi.org/10.1038/clpt.2012.237 |
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