Regulation of protein translation initiation in response to ionizing radiation

BACKGROUND: Proliferating tumor cells require continuous protein synthesis. De novo synthesis of most proteins is regulated through cap-dependent translation. Cellular stress such as ionizing radiation (IR) blocks cap-dependent translation resulting in shut-down of global protein translation which s...

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Detalles Bibliográficos
Autores principales: Trivigno, Donatella, Bornes, Laura, Huber, Stephan M, Rudner, Justine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577660/
https://www.ncbi.nlm.nih.gov/pubmed/23402580
http://dx.doi.org/10.1186/1748-717X-8-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577660/
https://www.ncbi.nlm.nih.gov/pubmed/23402580
http://dx.doi.org/10.1186/1748-717X-8-35

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