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Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells

The interplay between a non-lethal autophagic response and apoptotic cell death is still a matter of debate in cancer cell biology. In the present study performed on human melanoma cells, we investigate the role of basal or stimulated autophagy in cisplatin-induced cytotoxicity, as well as the contr...

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Detalles Bibliográficos
Autores principales: Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577730/
https://www.ncbi.nlm.nih.gov/pubmed/23437349
http://dx.doi.org/10.1371/journal.pone.0057236