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Calreticulin Induces Dilated Cardiomyopathy

BACKGROUND: Calreticulin, a Ca(2+)-buffering chaperone of the endoplasmic reticulum, is highly expressed in the embryonic heart and is essential for cardiac development. After birth, the calreticulin gene is sharply down regulated in the heart, and thus, adult hearts have negligible levels of calret...

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Detalles Bibliográficos
Autores principales: Lee, Dukgyu, Oka, Tatsujiro, Hunter, Beth, Robinson, Alison, Papp, Sylvia, Nakamura, Kimitoshi, Srisakuldee, Wattamon, Nickel, Barbara E., Light, Peter E., Dyck, Jason R. B., Lopaschuk, Gary D., Kardami, Elissavet, Opas, Michal, Michalak, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577809/
https://www.ncbi.nlm.nih.gov/pubmed/23437120
http://dx.doi.org/10.1371/journal.pone.0056387