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Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors

Activation of T cells through the engagement of the T cell receptors (TCRs) with specific peptide-MHC complexes on antigen presenting cells (APCs) is the major determinant for their proliferation, differentiation and display of effector functions. To assess the role of quantity and quality of peptid...

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Detalles Bibliográficos
Autores principales: Wan, Qi, Kozhaya, Lina, Imberg, Keren, Mercer, Frances, Zhong, Shi, Krogsgaard, Michelle, Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577812/
https://www.ncbi.nlm.nih.gov/pubmed/23437112
http://dx.doi.org/10.1371/journal.pone.0056302