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Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors
Activation of T cells through the engagement of the T cell receptors (TCRs) with specific peptide-MHC complexes on antigen presenting cells (APCs) is the major determinant for their proliferation, differentiation and display of effector functions. To assess the role of quantity and quality of peptid...
Autores principales: | Wan, Qi, Kozhaya, Lina, Imberg, Keren, Mercer, Frances, Zhong, Shi, Krogsgaard, Michelle, Unutmaz, Derya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577812/ https://www.ncbi.nlm.nih.gov/pubmed/23437112 http://dx.doi.org/10.1371/journal.pone.0056302 |
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