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Granulocyte Colony Stimulating Factor Induces Lipopolysaccharide (LPS) Sensitization via Upregulation of LPS Binding Protein in Rat

Liver is the main organ for lipopolysaccharide (LPS) clearance. Sensitization to LPS is associated with the upregulation of LPS-binding protein (LBP) in animal models. Therefore, we hypothesized that LBP could induce LPS sensitization through enhancing hepatic uptake of LPS. In this study, we examin...

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Detalles Bibliográficos
Autores principales: Fang, Haoshu, Liu, Anding, Sun, Jian, Kitz, Alexandra, Dirsch, Olaf, Dahmen, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577878/
https://www.ncbi.nlm.nih.gov/pubmed/23437199
http://dx.doi.org/10.1371/journal.pone.0056654