Gene Expression Analyses Implicate an Alternative Splicing Program in Regulating Contractile Gene Expression and Serum Response Factor Activity in Mice

Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CELFΔ transgenic mice, CELF splicing activity is inhibited postnatally in heart muscle via expression of a nuclear dominant negative CELF protein under an α-myosin heavy chain promoter. MHC-CELFΔ mice d...

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Detalles Bibliográficos
Autores principales: Dasgupta, Twishasri, Stillwagon, Samantha J., Ladd, Andrea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577904/
https://www.ncbi.nlm.nih.gov/pubmed/23437181
http://dx.doi.org/10.1371/journal.pone.0056590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577904/
https://www.ncbi.nlm.nih.gov/pubmed/23437181
http://dx.doi.org/10.1371/journal.pone.0056590

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