Improved Detection of Remote Homologues Using Cascade PSI-BLAST: Influence of Neighbouring Protein Families on Sequence Coverage

BACKGROUND: Development of sensitive sequence search procedures for the detection of distant relationships between proteins at superfamily/fold level is still a big challenge. The intermediate sequence search approach is the most frequently employed manner of identifying remote homologues effectivel...

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Detalles Bibliográficos
Autores principales: Kaushik, Swati, Mutt, Eshita, Chellappan, Ajithavalli, Sankaran, Sandhya, Srinivasan, Narayanaswamy, Sowdhamini, Ramanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577913/
https://www.ncbi.nlm.nih.gov/pubmed/23437136
http://dx.doi.org/10.1371/journal.pone.0056449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577913/
https://www.ncbi.nlm.nih.gov/pubmed/23437136
http://dx.doi.org/10.1371/journal.pone.0056449

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