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IL-1R signaling in dendritic cells replaces pattern recognition receptors to promote CD8(+) T cell responses to influenza A virus

Immune responses to vaccines require direct recognition of pathogen-associated molecular patterns (PAMPs) through pattern recognition receptors (PRRs) on dendritic cells (DCs). Unlike vaccines, infection by a live pathogen often impairs DC function and inflicts additional damage to the host. Here, w...

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Detalles Bibliográficos
Autores principales: Pang, Iris K., Ichinohe, Takeshi, Iwasaki, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577947/
https://www.ncbi.nlm.nih.gov/pubmed/23314004
http://dx.doi.org/10.1038/ni.2514