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IL-1R signaling in dendritic cells replaces pattern recognition receptors to promote CD8(+) T cell responses to influenza A virus
Immune responses to vaccines require direct recognition of pathogen-associated molecular patterns (PAMPs) through pattern recognition receptors (PRRs) on dendritic cells (DCs). Unlike vaccines, infection by a live pathogen often impairs DC function and inflicts additional damage to the host. Here, w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577947/ https://www.ncbi.nlm.nih.gov/pubmed/23314004 http://dx.doi.org/10.1038/ni.2514 |