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A new structural paradigm in copper resistance in Streptococcus pneumoniae

Copper resistance has emerged as an important virulence determinant of microbial pathogens. In Streptococcus pneumoniae, copper resistance is mediated by the copper-responsive repressor CopY, CupA, and CopA, a copper effluxing P(1B)-type ATPase. We show here that CupA is a novel cell membrane-anchor...

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Detalles Bibliográficos
Autores principales: Fu, Yue, Tsui, Ho-Ching Tiffany, Bruce, Kevin E., Sham, Lok-To, Higgins, Khadine A., Lisher, John P., Kazmierczak, Krystyna M., Maroney, Michael J., Dann, Charles E., Winkler, Malcolm E., Giedroc, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578076/
https://www.ncbi.nlm.nih.gov/pubmed/23354287
http://dx.doi.org/10.1038/nchembio.1168