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A new structural paradigm in copper resistance in Streptococcus pneumoniae
Copper resistance has emerged as an important virulence determinant of microbial pathogens. In Streptococcus pneumoniae, copper resistance is mediated by the copper-responsive repressor CopY, CupA, and CopA, a copper effluxing P(1B)-type ATPase. We show here that CupA is a novel cell membrane-anchor...
Autores principales: | Fu, Yue, Tsui, Ho-Ching Tiffany, Bruce, Kevin E., Sham, Lok-To, Higgins, Khadine A., Lisher, John P., Kazmierczak, Krystyna M., Maroney, Michael J., Dann, Charles E., Winkler, Malcolm E., Giedroc, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578076/ https://www.ncbi.nlm.nih.gov/pubmed/23354287 http://dx.doi.org/10.1038/nchembio.1168 |
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