Hairpin end conformation of adeno-associated virus (AAV) genome determines interactions with DNA repair pathways

The palindromic terminal repeats (TR) of adeno-associated virus (AAV) form DNA hairpins (HP) that are essential for replication and for priming the conversion of single-stranded virion DNA to double-strand. In recombinant AAV (rAAV) gene-delivery vectors, they are targets for DNA repair pathways lea...

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Detalles Bibliográficos
Autores principales: Cataldi, Marcela P., McCarty, Douglas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578132/
https://www.ncbi.nlm.nih.gov/pubmed/23151519
http://dx.doi.org/10.1038/gt.2012.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578132/
https://www.ncbi.nlm.nih.gov/pubmed/23151519
http://dx.doi.org/10.1038/gt.2012.86

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