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Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates

Influenza virus penetrates cells by fusion of viral and endosomal membranes catalyzed by the viral hemagglutinin (HA). Structures of the initial and final states of the HA trimer define the fusion endpoints, but do not specify intermediates. We have characterized these transitions by analyzing low-p...

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Detalles Bibliográficos
Autores principales: Ivanovic, Tijana, Choi, Jason L, Whelan, Sean P, van Oijen, Antoine M, Harrison, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578201/
https://www.ncbi.nlm.nih.gov/pubmed/23550179
http://dx.doi.org/10.7554/eLife.00333