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Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis

Aminoacyl-tRNA synthetases classically regulate protein synthesis but some also engage in alternative signaling functions related to immune responses and angiogenesis. Threonyl-tRNA synthetase (TARS) is an autoantigen in the autoimmune disorder myositis, and borrelidin, a potent inhibitor of TARS, i...

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Detalles Bibliográficos
Autores principales: Williams, Tamara F., Mirando, Adam C., Wilkinson, Barrie, Francklyn, Christopher S., Lounsbury, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578223/
https://www.ncbi.nlm.nih.gov/pubmed/23425968
http://dx.doi.org/10.1038/srep01317