Donor killer immunoglobulin-like receptor genes and reactivation of cytomegalovirus after HLA-matched hematopoietic stem-cell transplantation: HLA-C allotype is an essential cofactor

Natural killer (NK) cells whose killer immunoglobulin-like receptors (KIRs) recognize human leukocyte antigen (HLA) ligand are “licensed” for activity. In contrast, non-licensed NK cells display KIRs for which ligand is absent from the self genotype and are usually hyporesponsive. Surprisingly, non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Behrendt, Carolyn E., Nakamura, Ryotaro, Forman, Stephen J., Zaia, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578282/
https://www.ncbi.nlm.nih.gov/pubmed/23440333
http://dx.doi.org/10.3389/fimmu.2013.00036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578282/
https://www.ncbi.nlm.nih.gov/pubmed/23440333
http://dx.doi.org/10.3389/fimmu.2013.00036

Ejemplares similares