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New pockets in dengue virus 2 surface identified by molecular dynamics simulation

One of the factors limiting the search of new compounds based on the structure of target proteins involved in diseases is the limited amount of target structural information. Great advances in the search for lead compounds could be achieved to find new cavities in protein structures that are generat...

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Detalles Bibliográficos
Autores principales: Fuzo, Carlos A., Degrève, Léo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578724/
https://www.ncbi.nlm.nih.gov/pubmed/23197323
http://dx.doi.org/10.1007/s00894-012-1687-6