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The positional identity of mouse ES cell-generated neurons is affected by BMP signaling

We investigated the effects of bone morphogenetic proteins (BMPs) in determining the positional identity of neurons generated in vitro from mouse embryonic stem cells (ESCs), an aspect that has been neglected thus far. Classical embryological studies in lower vertebrates indicate that BMPs inhibit t...

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Detalles Bibliográficos
Autores principales: Bertacchi, Michele, Pandolfini, Luca, Murenu, Elisa, Viegi, Alessandro, Capsoni, Simona, Cellerino, Alessandro, Messina, Andrea, Casarosa, Simona, Cremisi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578729/
https://www.ncbi.nlm.nih.gov/pubmed/23069989
http://dx.doi.org/10.1007/s00018-012-1182-3