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The Caenorhabditis elegans JNK Signaling Pathway Activates Expression of Stress Response Genes by Derepressing the Fos/HDAC Repressor Complex

MAP kinases are integral to the mechanisms by which cells respond to a wide variety of environmental stresses. In Caenorhabditis elegans, the KGB-1 JNK signaling pathway regulates the response to heavy metal stress. In this study, we identified FOS-1, a bZIP transcription factor, as a target of KGB-...

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Detalles Bibliográficos
Autores principales: Hattori, Ayuna, Mizuno, Tomoaki, Akamatsu, Mayuko, Hisamoto, Naoki, Matsumoto, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578760/
https://www.ncbi.nlm.nih.gov/pubmed/23437011
http://dx.doi.org/10.1371/journal.pgen.1003315