Lactate Dehydrogenase-B Is Silenced by Promoter Methylation in a High Frequency of Human Breast Cancers

OBJECTIVE: Under normoxia, non-malignant cells rely on oxidative phosphorylation for their ATP production, whereas cancer cells rely on Glycolysis; a phenomenon known as the Warburg effect. We aimed to elucidate the mechanisms contributing to the Warburg effect in human breast cancer. EXPERIMENTAL D...

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Detalles Bibliográficos
Autores principales: Brown, Nicola J., Higham, Sue E., Perunovic, Branko, Arafa, Mohammad, Balasubramanian, Sabapathy, Rehman, Ishtiaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578788/
https://www.ncbi.nlm.nih.gov/pubmed/23437403
http://dx.doi.org/10.1371/journal.pone.0057697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578788/
https://www.ncbi.nlm.nih.gov/pubmed/23437403
http://dx.doi.org/10.1371/journal.pone.0057697

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