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Characterization of a Novel Mouse Model of Multiple Myeloma and Its Use in Preclinical Therapeutic Assessment

To aid preclinical development of novel therapeutics for myeloma, an in vivo model which recapitulates the human condition is required. An important feature of such a model is the interaction of myeloma cells with the bone marrow microenvironment, as this interaction modulates tumour activity and pr...

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Detalles Bibliográficos
Autores principales: Fryer, Rosemary A., Graham, Timothy J., Smith, Emma M., Walker-Samuel, Simon, Morgan, Gareth J., Robinson, Simon P., Davies, Faith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578800/
https://www.ncbi.nlm.nih.gov/pubmed/23437401
http://dx.doi.org/10.1371/journal.pone.0057641