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Characterization of a Novel Mouse Model of Multiple Myeloma and Its Use in Preclinical Therapeutic Assessment
To aid preclinical development of novel therapeutics for myeloma, an in vivo model which recapitulates the human condition is required. An important feature of such a model is the interaction of myeloma cells with the bone marrow microenvironment, as this interaction modulates tumour activity and pr...
Autores principales: | Fryer, Rosemary A., Graham, Timothy J., Smith, Emma M., Walker-Samuel, Simon, Morgan, Gareth J., Robinson, Simon P., Davies, Faith E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578800/ https://www.ncbi.nlm.nih.gov/pubmed/23437401 http://dx.doi.org/10.1371/journal.pone.0057641 |
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