MicroRNA-18a Attenuates DNA Damage Repair through Suppressing the Expression of Ataxia Telangiectasia Mutated in Colorectal Cancer

BACKGROUND: miR-18a is one of the most up-regulated miRNAs in colorectal cancers (CRC) based on miRNA profiling. In this study, we examined the functional significance of miR-18a in CRC. METHODS: Expression of miR-18a was investigated in 45 CRC patients. Potential target genes of miR-18a were predic...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Wah, Dong, Yu-Juan, Liang, Qiao-Yi, He, Xin-Qi, Ng, Simon S. M., Chan, Francis K. L., Sung, Joseph J. Y., Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578802/
https://www.ncbi.nlm.nih.gov/pubmed/23437304
http://dx.doi.org/10.1371/journal.pone.0057036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578802/
https://www.ncbi.nlm.nih.gov/pubmed/23437304
http://dx.doi.org/10.1371/journal.pone.0057036

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