Sensitivity of Malignant Peripheral Nerve Sheath Tumor Cells to TRAIL Is Augmented by Loss of NF1 through Modulation of MYC/MAD and Is Potentiated by Curcumin through Induction of ROS

Malignant peripheral nerve sheath tumor (MPNST) is a rare aggressive form of sarcoma often associated with the tumor syndrome neurofibromatosis type 1 (NF1). We investigated the effects of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) on NF1 associated MPNST and determinants of TRA...

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Detalles Bibliográficos
Autores principales: Reuss, David E., Mucha, Jana, Hagenlocher, Christian, Ehemann, Volker, Kluwe, Lan, Mautner, Victor, von Deimling, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578816/
https://www.ncbi.nlm.nih.gov/pubmed/23437333
http://dx.doi.org/10.1371/journal.pone.0057152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578816/
https://www.ncbi.nlm.nih.gov/pubmed/23437333
http://dx.doi.org/10.1371/journal.pone.0057152

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