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ABCD2 Is a Direct Target of β-Catenin and TCF-4: Implications for X-Linked Adrenoleukodystrophy Therapy

X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder caused by mutations in the ABCD1 gene that encodes the peroxisomal ATP-binding cassette (ABC) transporter subfamily D member 1 protein (ABCD1), which is referred to as the adrenoleukodystrophy protein (ALDP). Induction of the ABCD2 gene...

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Detalles Bibliográficos
Autores principales: Park, Chul-Yong, Kim, Han-Soo, Jang, Jiho, Lee, Hyunji, Lee, Jae Souk, Yoo, Jeong-Eun, Lee, Dongjin R., Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578850/
https://www.ncbi.nlm.nih.gov/pubmed/23437103
http://dx.doi.org/10.1371/journal.pone.0056242