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Inhibition of Pirfenidone on TGF-beta2 Induced Proliferation, Migration and Epithlial-Mesenchymal Transition of Human Lens Epithelial Cells Line SRA01/04

BACKGROUND: Posterior capsular opacification (PCO) is a common complication of cataract surgery. Transforming growth factor-β2 (TGF-β2) plays important roles in the development of PCO. The existing pharmacological treatments are not satisfactory and can have toxic side effects. METHODOLOGIES/PRINCIP...

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Detalles Bibliográficos
Autores principales: Yang, Yangfan, Ye, Yiming, Lin, Xianchai, Wu, Kaili, Yu, Minbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578851/
https://www.ncbi.nlm.nih.gov/pubmed/23437252
http://dx.doi.org/10.1371/journal.pone.0056837