Differential MicroRNA Regulation Correlates with Alternative Polyadenylation Pattern between Breast Cancer and Normal Cells

Alternative polyadenylation (APA) could result in mRNA isoforms with variable lengths of 3′ UTRs. Gain of microRNA target sites in the 3′ UTR of a long mRNA isoform may cause different regulation from the corresponding short isoform. It has been known that cancer cells globally exhibit a lower ratio...

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Detalles Bibliográficos
Autores principales: Liaw, Hao-Han, Lin, Chen-Ching, Juan, Hsueh-Fen, Huang, Hsuan-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578872/
https://www.ncbi.nlm.nih.gov/pubmed/23437281
http://dx.doi.org/10.1371/journal.pone.0056958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578872/
https://www.ncbi.nlm.nih.gov/pubmed/23437281
http://dx.doi.org/10.1371/journal.pone.0056958

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