ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement

The Hypoxia-inducible Factor (HIF) family of transcriptional regulators coordinates the expression of dozens of genes in response to oxygen deprivation. Mammalian development occurs in a hypoxic environment and HIF-null mice therefore die in utero due to multiple embryonic and placental defects. Mou...

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Detalles Bibliográficos
Autores principales: Choi, Hwa J., Sanders, Timothy A., Tormos, Kathryn V., Ameri, Kurosh, Tsai, Justin D., Park, Angela M., Gonzalez, Julissa, Rajah, Anthony M., Liu, Xiaowei, Quinonez, Diana M., Rinaudo, Paolo F., Maltepe, Emin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578927/
https://www.ncbi.nlm.nih.gov/pubmed/23437279
http://dx.doi.org/10.1371/journal.pone.0056949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578927/
https://www.ncbi.nlm.nih.gov/pubmed/23437279
http://dx.doi.org/10.1371/journal.pone.0056949

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