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ECM-Dependent HIF Induction Directs Trophoblast Stem Cell Fate via LIMK1-Mediated Cytoskeletal Rearrangement
The Hypoxia-inducible Factor (HIF) family of transcriptional regulators coordinates the expression of dozens of genes in response to oxygen deprivation. Mammalian development occurs in a hypoxic environment and HIF-null mice therefore die in utero due to multiple embryonic and placental defects. Mou...
Autores principales: | Choi, Hwa J., Sanders, Timothy A., Tormos, Kathryn V., Ameri, Kurosh, Tsai, Justin D., Park, Angela M., Gonzalez, Julissa, Rajah, Anthony M., Liu, Xiaowei, Quinonez, Diana M., Rinaudo, Paolo F., Maltepe, Emin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578927/ https://www.ncbi.nlm.nih.gov/pubmed/23437279 http://dx.doi.org/10.1371/journal.pone.0056949 |
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