In Vitro Characterization of Echinomycin Biosynthesis: Formation and Hydroxylation of L-Tryptophanyl-S-Enzyme and Oxidation of (2S,3S) β-Hydroxytryptophan

Quinoxaline-2-carboxylic acid (QXC) and 3-hydroxyquinaldic acid (HQA) feature in quinomycin family and confer anticancer activity. In light of the significant potency against cancer, the biosynthetic gene clusters have been reported from many different Streptomyces strains, and the biosynthetic path...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Kong, Lingxin, Liu, Qian, Lei, Xuan, Zhu, Tao, Yin, Jun, Lin, Birun, Deng, Zixin, You, Delin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578932/
https://www.ncbi.nlm.nih.gov/pubmed/23437232
http://dx.doi.org/10.1371/journal.pone.0056772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578932/
https://www.ncbi.nlm.nih.gov/pubmed/23437232
http://dx.doi.org/10.1371/journal.pone.0056772

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