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Holothurian Glycosaminoglycan Inhibits Metastasis and Thrombosis via Targeting of Nuclear Factor-κB/Tissue Factor/Factor Xa Pathway in Melanoma B16F10 Cells

Holothurian glycosaminoglycan (hGAG) is a high-molecular-weight form of fucosylated chondroitin sulfate and has an antithrombotic effect. Our previous studies demonstrated that hGAG efficiently inhibited tumor cell metastasis. The interplays between thrombosis and tumor progression may have a major...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Zhang, Daohai, Wang, Sheng, Tao, Li, Wang, Aiyun, Chen, Wenxing, Zhu, Zhijie, Zheng, Shizhong, Gao, Xiang, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578936/
https://www.ncbi.nlm.nih.gov/pubmed/23437168
http://dx.doi.org/10.1371/journal.pone.0056557