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Marqibo(®) (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine

Vincristine (VCR) is a mainstay of treatment of hematologic malignancies and solid tumors due to its well-defined mechanism of action, demonstrated anticancer activity and its ability to be combined with other agents. VCR is an M-phase cell cycle-specific anticancer drug with activity that is concen...

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Detalles Bibliográficos
Autores principales: Silverman, Jeffrey A., Deitcher, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579462/
https://www.ncbi.nlm.nih.gov/pubmed/23212117
http://dx.doi.org/10.1007/s00280-012-2042-4