Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study

PURPOSE: Acadesine has shown in vitro to selectively induce apoptosis in B cells from chronic lymphocytic leukemia (CLL) patients. We conducted a phase I/II open-label clinical study, to determine the safety and tolerability of acadesine given intravenously as a 4-h infusion to CLL patients. METHODS...

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Detalles Bibliográficos
Autores principales: Van Den Neste, Eric, Cazin, Bruno, Janssens, Ann, González-Barca, Eva, Terol, María José, Levy, Vincent, Pérez de Oteyza, Jaime, Zachee, Pierre, Saunders, Andrew, de Frias, Mercè, Campàs, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579463/
https://www.ncbi.nlm.nih.gov/pubmed/23228986
http://dx.doi.org/10.1007/s00280-012-2033-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579463/
https://www.ncbi.nlm.nih.gov/pubmed/23228986
http://dx.doi.org/10.1007/s00280-012-2033-5

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