Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects

BACKGROUND: Oxidative stress may lead to an increased level of unrepaired cellular DNA damage, which is discussed as one risk for tumor initiation. Mismatch repair (MMR) enzymes act as proofreading complexes that maintain the genomic integrity and MMR-deficient cells show an increased mutation rate....

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Detalles Bibliográficos
Autores principales: Switzeny, Olivier J, Müllner, Elisabeth, Wagner, Karl-Heinz, Brath, Helmut, Aumüller, Eva, Haslberger, Alexander G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579724/
https://www.ncbi.nlm.nih.gov/pubmed/23025454
http://dx.doi.org/10.1186/1868-7083-4-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579724/
https://www.ncbi.nlm.nih.gov/pubmed/23025454
http://dx.doi.org/10.1186/1868-7083-4-19

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