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Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects
BACKGROUND: Oxidative stress may lead to an increased level of unrepaired cellular DNA damage, which is discussed as one risk for tumor initiation. Mismatch repair (MMR) enzymes act as proofreading complexes that maintain the genomic integrity and MMR-deficient cells show an increased mutation rate....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579724/ https://www.ncbi.nlm.nih.gov/pubmed/23025454 http://dx.doi.org/10.1186/1868-7083-4-19 |