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Functional Capacity of Shiga-Toxin Promoter Sequences in Eukaryotic Cells

Shiga toxins (Stx) are the main virulence factors in enterohemorrhagic Escherichia coli (EHEC) infections, causing diarrhea and hemolytic uremic syndrome (HUS). The genes encoding for Shiga toxin-2 (Stx2) are located in a bacteriophage. The toxin is formed by a single A subunit and five B subunits,...

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Detalles Bibliográficos
Autores principales: Bentancor, Leticia V., Bilen, Marcos F., Mejías, María P., Fernández-Brando, Romina J., Panek, Cecilia A., Ramos, Maria V., Fernández, Gabriela C., Isturiz, Martín, Ghiringhelli, Pablo D., Palermo, Marina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579788/
https://www.ncbi.nlm.nih.gov/pubmed/23451160
http://dx.doi.org/10.1371/journal.pone.0057128