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Functional Capacity of Shiga-Toxin Promoter Sequences in Eukaryotic Cells
Shiga toxins (Stx) are the main virulence factors in enterohemorrhagic Escherichia coli (EHEC) infections, causing diarrhea and hemolytic uremic syndrome (HUS). The genes encoding for Shiga toxin-2 (Stx2) are located in a bacteriophage. The toxin is formed by a single A subunit and five B subunits,...
Autores principales: | Bentancor, Leticia V., Bilen, Marcos F., Mejías, María P., Fernández-Brando, Romina J., Panek, Cecilia A., Ramos, Maria V., Fernández, Gabriela C., Isturiz, Martín, Ghiringhelli, Pablo D., Palermo, Marina S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579788/ https://www.ncbi.nlm.nih.gov/pubmed/23451160 http://dx.doi.org/10.1371/journal.pone.0057128 |
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