Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells

The CD11b/CD18 integrin (complement receptor 3, CR3) is a surface receptor on monocytes, neutrophils, macrophages and dendritic cells that plays a crucial role in several immunological processes including leukocyte extravasation and phagocytosis. The minor allele of a non-synonymous CR3 polymorphism...

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Detalles Bibliográficos
Autores principales: Fossati-Jimack, Liliane, Ling, Guang Sheng, Cortini, Andrea, Szajna, Marta, Malik, Talat H., McDonald, Jacqueline U., Pickering, Matthew C., Cook, H. Terence, Taylor, Philip R., Botto, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579793/
https://www.ncbi.nlm.nih.gov/pubmed/23451151
http://dx.doi.org/10.1371/journal.pone.0057082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579793/
https://www.ncbi.nlm.nih.gov/pubmed/23451151
http://dx.doi.org/10.1371/journal.pone.0057082

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