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Neutralizing Antibodies Induced by Recombinant Virus-Like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps

BACKGROUND: Enterovirus 71 (EV71) is a major causative agent of hand, foot and mouth disease, which has been prevalent in Asia–Pacific regions, causing significant morbidity and mortality in young children. Antibodies elicited by experimental EV71 vaccines could neutralize infection in vitro and pas...

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Detalles Bibliográficos
Autores principales: Ku, Zhiqiang, Ye, Xiaohua, Huang, Xulin, Cai, Yicun, Liu, Qingwei, Li, Yan, Su, Zhiguo, Huang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579802/
https://www.ncbi.nlm.nih.gov/pubmed/23451250
http://dx.doi.org/10.1371/journal.pone.0057601