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Dissociated Primary Human Prostate Cancer Cells Coinjected with the Immortalized Hs5 Bone Marrow Stromal Cells Generate Undifferentiated Tumors in NOD/SCID-γ Mice

Reconstitution of tumor development in immunodeficient mice from disaggregated primary human tumor cells is always challenging. The main goal of the present study is to establish a reliable assay system that would allow us to reproducibly reconstitute human prostate tumor regeneration in mice using...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Liu, Bigang, Li, Qiuhui, Honorio, Sofia, Liu, Xin, Liu, Can, Multani, Asha S., Calhoun-Davis, Tammy, Tang, Dean G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579939/
https://www.ncbi.nlm.nih.gov/pubmed/23451107
http://dx.doi.org/10.1371/journal.pone.0056903