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Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

BACKGROUND: Cells sense the extracellular environment using adhesion receptors (integrins) linked to the intracellular actin cytoskeleton through a complex network of regulatory proteins that, all together, form focal adhesions (FAs). The molecular basis of how these sensing units are regulated, how...

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Detalles Bibliográficos
Autores principales: Carisey, Alex, Tsang, Ricky, Greiner, Alexandra M., Nijenhuis, Nadja, Heath, Nikki, Nazgiewicz, Alicja, Kemkemer, Ralf, Derby, Brian, Spatz, Joachim, Ballestrem, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580286/
https://www.ncbi.nlm.nih.gov/pubmed/23375895
http://dx.doi.org/10.1016/j.cub.2013.01.009