CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

Gene regulation by cytokine-activated transcription factors of the signal transducer and activator of transcription (STAT) family requires serine phosphorylation within the transactivation domain (TAD). STAT1 and STAT3 TAD phosphorylation occurs upon promoter binding by an unknown kinase. Here, we s...

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Detalles Bibliográficos
Autores principales: Bancerek, Joanna, Poss, Zachary C., Steinparzer, Iris, Sedlyarov, Vitaly, Pfaffenwimmer, Thaddäus, Mikulic, Ivana, Dölken, Lars, Strobl, Birgit, Müller, Mathias, Taatjes, Dylan J., Kovarik, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580287/
https://www.ncbi.nlm.nih.gov/pubmed/23352233
http://dx.doi.org/10.1016/j.immuni.2012.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580287/
https://www.ncbi.nlm.nih.gov/pubmed/23352233
http://dx.doi.org/10.1016/j.immuni.2012.10.017

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