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CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response
Gene regulation by cytokine-activated transcription factors of the signal transducer and activator of transcription (STAT) family requires serine phosphorylation within the transactivation domain (TAD). STAT1 and STAT3 TAD phosphorylation occurs upon promoter binding by an unknown kinase. Here, we s...
Autores principales: | Bancerek, Joanna, Poss, Zachary C., Steinparzer, Iris, Sedlyarov, Vitaly, Pfaffenwimmer, Thaddäus, Mikulic, Ivana, Dölken, Lars, Strobl, Birgit, Müller, Mathias, Taatjes, Dylan J., Kovarik, Pavel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580287/ https://www.ncbi.nlm.nih.gov/pubmed/23352233 http://dx.doi.org/10.1016/j.immuni.2012.10.017 |
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