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Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies

BACKGROUND: The advent of personalized medicine requires robust, reproducible biomarkers that indicate which treatment will maximize therapeutic benefit while minimizing side effects and costs. Numerous molecular signatures have been developed over the past decade to fill this need, but their valida...

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Detalles Bibliográficos
Autores principales: Starmans, Maud HW, Pintilie, Melania, John, Thomas, Der, Sandy D, Shepherd, Frances A, Jurisica, Igor, Lambin, Philippe, Tsao, Ming-Sound, Boutros, Paul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580418/
https://www.ncbi.nlm.nih.gov/pubmed/23146350
http://dx.doi.org/10.1186/gm385