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Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?
Parkinson's disease, the most common movement disorder, results in an insidious reduction for patients in quality of life and ability to function. A hallmark of Parkinson's disease is the brain accumulation of neuronal cytoplasmic inclusions comprised of the protein α-synuclein. The presen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580457/ https://www.ncbi.nlm.nih.gov/pubmed/23245350 http://dx.doi.org/10.1186/alzrt151 |