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Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?

Parkinson's disease, the most common movement disorder, results in an insidious reduction for patients in quality of life and ability to function. A hallmark of Parkinson's disease is the brain accumulation of neuronal cytoplasmic inclusions comprised of the protein α-synuclein. The presen...

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Detalles Bibliográficos
Autores principales:	Sacino, Amanda N, Giasson, Benoit I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580457/ https://www.ncbi.nlm.nih.gov/pubmed/23245350 http://dx.doi.org/10.1186/alzrt151

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